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1.3.23Board Correspondence - FW_ Inflammation and Autophagy_ A Convergent Point between Autism Spectrum Disorder (ASD)-Related Genetic and Environm…
.ATTENTION: This message originated from outside Butte County. Please exercise judgment before opening attachments, clicking on links, or replying.. From:Clerk of the Board To:Nuzum, Danielle; Reaster, Kayla; Boatwright, JPSubject:Board Correspondence - FW: Inflammation and Autophagy: A Convergent Point between Autism Spectrum Disorder (ASD)-Related Genetic and Environm… Date:Tuesday, January 3, 2023 7:59:23 AM Shaina Paulsen Associate Clerk of The Board Butte County Administration 25 County Center Drive, Suite 200, Oroville, CA 95965 T: 530.552.3304 | F: 530.538.7120 From: lance dreiss <lancedreiss@att.net> Sent: Tuesday, January 3, 2023 12:07 AM To: District Attorney <District_Attorney@buttecounty.net>; York, Danette <DYork@buttecounty.net>; Connelly, Bill <BConnelly@buttecounty.net>; Ring, Brian <bring@buttecounty.net>; Kimmelshue, Tod <TKimmelshue@buttecounty.net>; Pickett, Andy <APickett@buttecounty.net>; Waugh, Melanie <mwaugh@buttecounty.net>; Ritter, Tami <TRitter@buttecounty.net>; Lucero, Debra <DLucero@buttecounty.net>; Teeter, Doug <DTeeter@buttecounty.net>; JULIE THREET <prayinghawk144@gmail.com>; Clerk of the Board <clerkoftheboard@buttecounty.net>; Stephens, Brad J. <BStephens@buttecounty.net> Subject: Fwd: Inflammation and Autophagy: A Convergent Point between Autism Spectrum Disorder (ASD)-Related Genetic and Environm… I hope this tragedy will be the downfall of all vaccines. I told you if you look you will find the truth. It’s there for all to see.Trying to bully parents not to think for themselves, and do what is best for their sweet babies, by calling them anti vaxx Is EVIL! I’m anti vaxx and proud of it. You can’t bully me. YOU disgust me. diana dreissSent from my iPad Begin forwarded message: From: James Lyons-Weiler from Popular Rationalism <popularrationalism@substack.com>Date: January 2, 2023 at 5:46:23 AM PSTTo: lancedreiss@att.netSubject: Inflammation and Autophagy: A Convergent Point between Autism Spectrum Disorder (ASD)-Related Genetic and Environm…Reply-To: James Lyons-Weiler from Popular Rationalism<reply+1k3urh&kcryl&&4e2a656a1d7d6b72cd46eb2644d326c7ee6ce3b4683fb89164ba505c660ae6ea@mg1.substack.com> A New Review Highlights What the Science Actually Shows Open in app or online #PopularRationalism Inflammation and Autophagy: A Convergent Pointbetween Autism Spectrum Disorder (ASD)-RelatedGenetic and Environmental Factors: Focus onAluminum Adjuvants A New Review Highlights What the Science Actually Shows JAMES LYONS-WEILER JAN 2 SAVE ▷ LISTEN …the role of early inflammation, immune and autophagy dysfunction in ASD as well as preclinical studies which question Al adjuvant impacts on brain and immune maturation. Pubmed Link Abstract Autism spectrum disorder (ASD), schizophrenia, and bipolar disorder are genetically complex and heterogeneous neurodevelopmental disorders (NDDs) resulting from genetic factors and gene-environment (GxE) interactions for which onset occurs in early brain development. Recent progress highlights the link between ASD and (i) immunogenetics, neurodevelopment, and inflammation, and (ii) impairments of autophagy, a crucial neurodevelopmental process involved in synaptic pruning. Among various environmental factors causing risk for ASD, aluminum (Al)-containing vaccines injected during critical periods have received special attention and triggered relevant scientific questions. The aim of this review is to discuss the current knowledge on the role of early inflammation, immune and autophagy dysfunction in ASD as well as preclinical studies which question Al adjuvant impacts on brain and immune maturation. We highlight the most recent breakthroughs and the lack of epidemiological, pharmacokinetic and pharmacodynamic data constituting a "scientific gap". We propose additional research, such as genetic studies that could contribute to identify populations at genetic risk, improving diagnosis, and potentially the development of new therapeutic tools. Keywords: aluminum adjuvants; autism spectrum disorder; autophagy; early exposure; environment; immune system; neurodevelopmental disorders; neurotoxicity. Angrand L, Masson JD, Rubio-Casillas A, Nosten-Bertrand M, Crépeaux G. Inflammation and Autophagy: A Convergent Point between Autism Spectrum Disorder (ASD)-Related Genetic and Environmental Factors: Focus on Aluminum Adjuvants. Toxics. 2022 Aug 31;10(9):518. doi: 10.3390/toxics10090518. PMID: 36136483; PMCID: PMC9502677. Upgrade to paid Leave a comment IPAK Autism Model Thank you for being a subscriber to Popular Rationalism. For the full experience, become a paying subscriber. And check out our awesome, in-depth, live full semester courses at IPAK-EDU. Hope to see you in class! Upgrade to paid LIKE COMMENT SHARE Read Popular Rationalism in the app Listen to posts, join subscriber chats, and never miss an update from James Lyons-Weiler. © 2023 James Lyons-Weiler20714 Shady Lane Ave, Shady Lane, St. Clair Shores, MI 48080 Unsubscribe