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HomeMy WebLinkAbout11.30.25 Board Correspondence - FW_ The Calamari Clots_ Why the White Clots May Be the Smoking Gun of the mRNA Era..ATTENTION: This message originated from outside Butte County. Please exercise judgment before opening attachments, clicking on links, or replying.. From:Clerk of the Board To:Mutony, Heather Cc:Lee, Lewis Subject:Board Correspondence - FW: The Calamari Clots: Why the White Clots May Be the Smoking Gun of the mRNA Era. Date:Wednesday, December 3, 2025 11:03:03 AM Attachments:https%3A%2F%2Fsubstack-post-media.s3.amazonaws.com%2Fpublic%2Fimages%2F15edc823-12a4-4118-900a-7a03500bcd42_1277x1277.png https%3A%2F%2Fsubstack.com%2Ficon%2FLucideHeart%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2 https%3A%2F%2Fsubstack.com%2Ficon%2FLucideComments%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2 https%3A%2F%2Fsubstack.com%2Ficon%2FLucideShare2%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2 https%3A%2F%2Fsubstack.com%2Ficon%2FNoteForwardIcon%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2 https%3A%2F%2Fsubstack.com%2Ficon%2FLucideArrowUpRight%3Fv%3D4%26height%3D36%26fill%3Dnone%26stroke%3D%2523808080%26strokeWidth%3D2 Please see Board Correspondence - From: lance dreiss <lancedreiss@att.net> Sent: Sunday, November 30, 2025 5:06 PM To: Shared Mailbox Clerk of the Board <pcbs@countyofplumas.com>; Soderstrom, Monica <msoderstrom@buttecounty.net>; Assemblymember.Gallagher@assembly.ca.gov; Senator.Dahle@senate.ca.gov; davidhollister@countyofplumas.com; sheriff@countyofplumas.com; District Attorney <District_Attorney@buttecounty.net>; Kimmelshue, Tod <TKimmelshue@buttecounty.net>; Pickett, Andy <APickett@buttecounty.net>; Connelly, Bill <BConnelly@buttecounty.net>; Teeter, Doug <DTeeter@buttecounty.net>; Julie Threet <julie4butte5@gmail.com>; Waugh, Melanie <mwaugh@buttecounty.net>; Kitts, Melissa <mkitts@buttecounty.net>; Durfee, Peter <PDurfee@buttecounty.net>; Ritter, Tami <TRitter@buttecounty.net>; Teri DuBose <Teri.DuBose@mail.house.gov>; Congressman Doug LaMalfa <CA01DL.Outreach@mail.house.gov>; Stephens, Brad J. <BStephens@buttecounty.net>; Clerk of the Board <clerkoftheboard@buttecounty.net> Subject: Fwd: The Calamari Clots: Why the White Clots May Be the Smoking Gun of the mRNA Era. Public Record Forwarded this email? Subscribe here for moreThe Calamari Clots: Why the White Clots May Be the Smoking Gun of the mRNA Era. Quirks in mRNA vaccines that make them biologically plausible culprits DANIEL SANTIAGO RPH, PHARMD NOV 30 READ IN APP “*Image provided by Richard Hirschman You’ve seen the photos: foot-long, rubbery white filaments pulled from veins during autopsies. Embalmers worldwide, veterans with 30+ years on the job, say these “calamari clots” are new since 2021.” diana dreiss Begin forwarded message: From: "DANIEL SANTIAGO RPh, PharmD from DANIEL’s Substack" <santiagod@substack.com> Date: November 30, 2025 at 1:28:59 PM PST To: lancedreiss@att.net Subject: The Calamari Clots: Why the White Clots May Be the Smoking Gun of the mRNA Era. Reply-To: DANIEL SANTIAGO RPh, PharmD from DANIEL’s Substack <reply+2zd089&kcryl&&20b7442f4eb045c22959193a0d00fdc6bd005e221af1df9f7e086295996ab1d6@mg1.substack.com>  Quirks in mRNA vaccines that make them biologically plausible culprits͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­͏   ­Forwarded this email? Subscribe hereThe Calamari Clots: Why the White Clots May Be the Smoking Gun of the mRNA Era. Quirks in mRNA vaccines that make them biologically plausible culprits DANIEL SANTIAGO RPH, PHARMD NOV 30 READ IN APP *Image provided by Richard Hirschman You’ve seen the photos: foot-long, rubbery white filaments pulled from veins during autopsies. Embalmers worldwide, veterans with 30+ years on the job, say these “calamari clots” are new since 2021. Thanks for reading DANIEL’s Substack! Subscribe for free to receive new posts and support my work. Pledge your support *Image provided by Richard Hirschman Mainstream media and fact-checkers immediately labelled these reports ‘anecdotal’ and moved on. The peer-reviewed literature certainly has not. Three independent discoveries, now etched in the literature, expose flaws in the mRNA platform and a dark property of the spike protein itself. 1. Covalent lipid–mRNA adducts are real and were not quantified in released lots (Packer 2021) Reactive breakdown products of the ionizable lipid irreversibly attach to the mRNA bases, creating novel chemical entities. These adducts are: •Translated poorly, not at all, or produce random truncations. • Invisible to capillary electrophoresis. So, how much was in any shipped vial? • Levels rise with storage time, temperature, and poorer lipid purity. Every shipped vial contained some percentage of these damaged mRNAs • To my knowledge, the exact amount per lot has never been publicly disclosed. 2. N¹-methylpseudouridine drives +1 ribosomal frameshifting in ~8–10 % of translation events in human cells and in vaccinated individuals.(Mulroney 2023) This produces a subpopulation of misfolded spike proteins (terminated by an out-of-frame stop). These frameshifted proteins are immunogenic garbage that were never tested pre- clinically. Contemplate the analogy of sugar in a gas tank. 3. Certain short peptides within spike are amyloidgenic. (Nyström 2022) Proteases can be massively elevated at sites of inflammation or endothelial damage (neutrophil elastase, plasmin, cathepsins) and can cleave spike and expose amyloidogenic segments. Pre-formed fibrils of these exact peptides bind fibrinogen, create abnormally dense fibrin networks, and block fibrinolysis in purified in vitro systems. The phenomena is real. The biologically plausible (but still unproven) pathway to the white clots • Aberrant spike products (lipid-adducted, frameshifted, or proteolytically nicked) are generated at industrial scale in some vaccinated persons. • At sites of inflammation or endothelial damage, proteases can liberate the exact amyloidogenic spike peptides shown to cause resistant microclots in purified in vitro systems. • Large, white, rubbery postmortem clots have been documented by embalmers and physicians worldwide since 2021. Their temporal appearance tracks vaccination campaigns far better than infection waves. What is still missing to prove causation • Public lot-by-lot quantitation of lipid–mRNA adduct levels in commercial vials. • Mass spectrometry or immunohistochemistry of the actual white fibrous clots showing presence (or absence) of spike-derived amyloidogenic peptides. • An animal model combining realistic adduct + frameshift levels with inflammation that reproduces the macroscopic clot pathology. Until those experiments are done, the most accurate one-sentence summary of the peer-reviewed literature in November 2025 is: “The mRNA platform unavoidably produces aberrant spike proteins, and inflammatory proteases can convert spike into amyloidogenic peptides that multiple independent labs have proven can cause resistant microclots in vitro, making spike-derived amyloid the single most parsimonious explanation for the white fibrous clots that remains completely untested in the actual postmortem material.” The clots are real. The chemistry is real. This isn’t conspiracy. It’s chemistry begging for answers. Release the data. Sequence the clots. Test it. The dead deserve it. We all do. Share if you’ve seen the photos. Comment References: Clotastrophe Results of the 2024 Worldwide Embalmer Blood Clot Survey Results of Our Third Annual Survey (written with the assistance of Tom Haviland… Read more a year ago · 311 likes · 123 comments · Laura Kasner Bhatt, P. R., Scaiola, A., Loughran, G., Leibundgut, M., Kratzel, A., Meurs, R., Dreos, R., O’Connor, K. M., McMillan, A., Bode, J. W., Thiel, V., Gatfield, D., Atkins, J. F., & Ban, N. (2021). Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science (New York, N.Y.), 372(6548), 1306–1313. https://doi.org/10.1126/science.abf3546 Grobbelaar, L. M., Venter, C., Vlok, M., Ngoepe, M., Laubscher, G. J., Lourens, P. J., Steenkamp, J., Kell, D. B., & Pretorius, E. (2021). SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19. Bioscience reports, 41(8), BSR20210611. https://doi.org/10.1042/BSR20210611 Nyström, S., & Hammarström, P. (2022). Amyloidogenesis of SARS-CoV-2 spike protein. Journal of the American Chemical Society, 144(20), 8945–8950. https://doi.org/10.1021/jacs.2c03925 Mulroney, T. E., Pöyry, T., Yam-Puc, J. C., Rust, M., Harvey, R. F., Kalmar, L., … Willis, A. E. (2024). N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting. Nature, 625(7993), 189–194. https://doi.org/10.1038/s41586-023-06800-3 Packer, M., Gyawali, D., Yerabolu, R., Schariter, J., & White, P. (2021). A novel mechanism for the loss of mRNA activity in lipid nanoparticle delivery systems. Nature communications, 12(1), 6777. https://doi.org/10.1038/s41467-021-26926-0 Correlation Is Not Causation, Except When It Is: Lessons from Thalidomide, Smoking, Asbestos,and mRNA Vaccine Concerns DANIEL SANTIAGO RPH, PHARMD ·JUN 5 Correlation Is Not Causation, Except When It Is: Lessons from Thalidomide, Smoking, Asbestos, and mRNA Vaccine Concerns The Mantra: Correlation Does Not Imply Causation Read full story Thierry, A. R., Usher, T., Sanchez, C., Turner, S., Venter, C., Pastor, B., Waters, M., Thompson, A., Mirandola, A., Pisareva, E., Prevostel, C., Laubscher, G. J., Kell, D. B., & Pretorius, E. (2025). Circulating Microclots Are Structurally Associated With Neutrophil Extracellular Traps and Their Amounts Are Elevated in Long COVID Patients. Journal of medical virology, 97(10), e70613. https://doi.org/10.1002/jmv.70613 Westman, Henrik; Hammarström, Per; Nyström, Sofie (2025). SARS-CoV‑2 Spike Protein Amyloid Fibrils Impair Fibrin Formation and Fibrinolysis. ACS Publications. Collection. https://doi.org/10.1021/acs.biochem.5c00550 Thanks for reading DANIEL’s Substack! Subscribe for free to receive new posts and support my work. Pledge your support DANIEL’s Substack is free today. But if you enjoyed this post, you can tell DANIEL’s Substack that their writing is valuable by pledging a future subscription. You won't be charged unless they enable payments. Pledge your support LIKE COMMENT RESTACK © 2025 DANIEL SANTIAGO548 Market Street PMB 72296, San Francisco, CA 94104 Unsubscribe